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« Postdoc - Statistical Genomics Recombination, Max Planck Institute for Developmental Biology - Germany | Main | Research Officer - Walter and Eliza Hall Institute »
Tuesday
Apr152014

PhD - Evolutionary Genomics of Recombination, Max Planck Institute for Developmental Biology - Germany

Recombination Hotspots & Adaptive Evolution

We are looking for enthusiastic and team-spirited researchers to join the Jones Lab at the Max Planck Institute in Tuebingen Germany as part of a prestigious 2M€ European Research Council funded grant investigating the role of meiotic recombination in adaptive evolution.

We study the molecular mechanisms underlying adaptive evolution and speciation. The goal of this particular project is to use cutting-edge techniques to characterize, quantify, map and manipulate meiotic recombination hotspots at unprecedented resolution across the genome, among individuals, and between species. We will map the genetic basis of recombination modifiers and study the effects of recombination variation on individual fitness in the lab and field. This ground-breaking research will elucidate how a fundamental biological process shapes the genomic basis of adaptive divergence in natural populations.

Your role:  You will provide a comprehensive view of genetic factors underlying variation in recombination and its role in adaptive evolution. Your research will comprise both computational (dry) and experimental (wet) components. For computational work you will be responsible for genetically mapping variation in recombination hotspots in F2 families using whole genome sequence data, and searching for genomic features associated with recombination hot- and coldspots. In the wetlab you will work on functionally dissecting hotspot modifiers, and study the fitness consequences of recombination between adaptive loci in lab and natural populations.

Requirements:  You will have a Masters or equivalent degree in the area of genetics, bioinformatics, molecular biology and/or evolution. We are looking for person with training in molecular biology techniques such as cloning, library preparation, fluorescent in situ hybridisation, and computational genomic methods including experience with unix and coding in C, python, perl, or R. The successful candidate will demonstrate a passion to study genetics and the molecular mechanisms of evolution.

Our Team:  You will work in a multidisciplinary team that uses population genomics, genetics, molecular, developmental, and evolutionary biology to study the molecular mechanisms underlying adaptation and speciation in the threespine stickleback fish. Our research group is funded by the European Research Council (ERC) and the Max Planck Society and is located on the Max Planck campus in Tuebingen, Germany. Our campus hosts world-class research groups, including 7 other ERC-funded teams, and operates state-of-the-art sequencing and other core facilities. English is the working language. All seminars and communications are in English.

Our Offer:  The position is for three years. Salary and benefits are according to the German public service pay scale (TVöD Bund).

The Max Planck Society seeks to increase the number of women in areas, where they are underrepresented, and therefore explicitly encourages women to apply. Disabled applicants with equal qualifications will be given preferential treatment.

To Apply:  Consideration of applications will begin on April 15th 2014, and will remain open until filled.  Please send your application with 1. a statement of research interests and why you have applied for this position, 2. your CV, and 3. three reference letters to Dr Felicity Jones at fcjones@tuebingen.mpg.de or the postal address below.  Incomplete applications will not be considered.   

Dr Felicity Jones, Friedrich Miescher Laboratory of the Max Planck Society, Spemannstrasse 39, 72076 Tuebingen, Germany.

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