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« Research Fellow / Senior Research Fellow (Biostatistics) – University of Sydney | Main | Bioinformatician (Computational Systems Biology) – University of Melbourne »

Research Fellow in Computational Biostatistics - University of Melbourne

The Centre for Stem Cell Systems is seeking a skilled and experienced research fellow to work on our exciting Mesenchymal Stromal Cells subtype classification project. Human Mesenchymal Stromal Cells (MSC) are rare multipotent cells that are being increasingly adopted in cell therapy. However, they are poorly defined and difficult to isolate from other stromal or blood cells. Work on this project has involved the review, collation and curation of hundreds of datasets on MSC source, growth, differentiation capacity and associated donor properties. This is the largest international collection of curated MSC data, which are available through our stem cell data repository By focussing on studies with whole-transcriptome profiling and high quality associated phenotypic data, we have developed a statistical method to identify a reliable gene signature to classify “MSC” versus other cell types (; Rohart et al. 2016).

The role will be responsible for leading novel and innovative statistical developments in stem cell research to understand the identity, heterogeneity and therapeutic potential of MSC. The successful applicant will work in close interaction with stem cell laboratory researchers, bioinformaticians and statisticians in this initiative.

The position will be based at the Centre for Stem Cell Systems in the Department of Anatomy and Neuroscience and will primarily report to the Centre Director, Professor Christine Wells. The successful candidate will also work under direction of Dr Kim-Anh Lê Cao in the Centre for Systems Genomics.

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