The Human Comparative and Prostate Cancer Genomics Laboratory is looking for a PhD candidate looking to undertake a study focused on the identification and categorization of genomic variations, particularly structural variants, driving prostate cancer outcomes. Somatic (non-inherited) structural variation involving large genome rearrangements is a significant driver of prostate cancer heterogeneity and evolution. Unlike single nucleotide DNA variations, large structural variants are harder to accurately detect. The PhD candidate will focus on the implementation and development of statistical/computational tools to screen and merge DNA sequencing and mapping data generated using a number of next generation sequencing platforms to identify large structural variations associated with prostate cancer. Data will be generated within the laboratory and merged with publically available datasets.